IBP Network Webinar: Dr Enrico Dall’Ara - Finite element models for bone applications at different dimensional scales: validation with digital volume correlation
Date: 14 April 2021 Time: 15:00 - 16:00
Finite Element (FE) models are powerful tools to predict the bone properties of different biological tissues. In the past decades they have been used to evaluate the effect of musculoskeletal diseases and related interventions on the structural mechanical properties of different bones. Nevertheless, before their clinical application, we have to provide the adequate credibility to the models through a meticulous process of verification, validation and uncertainties quantification. The predictions of the models for the bone’s structural mechanical properties (e.g. stiffness and strength) can be validated with standard mechanical tests in the laboratory. However, the validation of the local displacements and strains under certain loading conditions, fundamental to understand the heterogeneous response to a disease or an intervention, is not trivial. The development of full field strain measurement technique by using a combination of imaging, image processing and Digital Image or Digital Volume Correlation algorithms has allowed us to push the validation of the outputs of the FE models of complex bone structures to the next level. In this webinar I will provide an overview of the full field experimental and imaging techniques that can be used to test the ability of FE models for different bone structures in predicting local displacements and strains, with a particular focus on the application of Digital Volume Correlation as validation tool.
About the speaker:
Dr Enrico Dall’Ara is a Senior Lecturer at the Department of Oncology and Metabolism and Insigneo Institute of in silico Medicine, at the University of Sheffield.
He has received a degree in Mechanical Engineering from the University of Bologna (2006) and a PhD in Biomechanics from the Vienna University of Technology (2012). He then moved to the University of Sheffield as was Marie-Curie fellow (2013-2015) and was appointed Lecturer in 2015 and Senior Lecturer in 2019. His research interests are the development and validation of in silico approaches for improving preclinical and clinical assessment of interventions for musculoskeletal diseases. He has published 80 papers in international journals (>1700 citations, h-index 23) and his research has been funded by the EU, NC3Rs, EPSRC, BBSRC, Royal Society, and SFTC. Enrico is on the council of the European Society of Biomechanics and is the president of the UK chapter of the Virtual Physiological Human institute.
About IBP Network Webinar Series:
- Open to all IBP Network members. (Not a member? Join here)
- To bring together members of our community.
- Talks from eminent scientists, beamline scientists and facility specialists across the world.
- 30 – 45 minutes talk followed by 5-15 minutes Q&A.
- Talk will be recorded (except the Q&A) and made available to all network members.
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